UFJF - Universidade Federal de Juiz de Fora

BioInorganic Chemistry

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Our research line – BioInorganic Chemistry, started on ending 2007. Our BioInorganic research has been concentrated on metal complexes, especially with Ag+, Zn2+, VO2+ and Au+/3+ ions with organic compounds. Our organic syntheses have been focused on condensation between aliphatic and aromatic amines, sulfonamides and amino acids, isoniazid, pyraminazide, nicotinamide and other with natural aldehydes.

Metal complexes are active against gram positive and negative bacteria, mycobacteria, especially against M. tuberculosis, and some of them are have anticancer properties. In addition, some complexes, specifically, vanadium ones, were tested against Leishamina and excellent outcomes have been reached.