Laboratório de Desenvolvimento de Sistemas Nanoestruturados

Published papers

2022

FREITAS, P. ; CONEGUNDES, J. L. M. ; EVANGELISTA, M. R. ; ALMEIDA, M. A. ; SILVA, Natália Prado da ; TAVARES, G. D. ; VILELA, Fernanda Maria Pinto ; RIBEIRO, A. ; DUQUE, A. P. N. ; SCIO, E. . Cecropia pachystachya Trécul: a promising ingredient for skin-whitening cosmetics. Brazilian Journal of Pharmaceutical Sciences, 2022.

SANTOS, J. S. ; BARRADAS, T. N. ; TAVARES, G. D. . Improvement of hair-related disorders by nanotechnologybased hair care products. International Journal of Cosmetic Science, 2022.

2021

JAEGER, LAUREN HUBERT ; NASCIMENTO, THIAGO CÉSAR ; ROCHA, FABÍOLA DUTRA ; VILELA, FERNANDA MARIA PINTO ; DUQUE, ANA PAULA DO NASCIMENTO ; SILVA, LÍVIA MARA ; RIANI, LORENA RODRIGUES ; MOREIRA, JOÃO PAULO ; CHAGAS, JÉSSICA MARA DE ASSIS ; PEREIRA, THAMIRIS VILELA ; PERCHES, CARMEN GOMIDE PINTO ; WATANABE, ARIPUANA SAKURADA ARANHA ; VICCINI, LYDERSON FACIO ; SILVÉRIO, MARCELO SILVA ; CORRÊA, JOSÉ OTÁVIO DO AMARAL ; PEREIRA-JUNIOR, OLAVO DOS SANTOS ; PITTELLA, Frederico . Adjusting RT-qPCR conditions to avoid unspecific amplification in SARS-CoV-2 diagnosis. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, v. 102, p. 437-439, 2021.

SOUZA, GABRIELA REGINA ROSA ; DALMINA, MILENE ; RESTREPO, JELVER ALEXANDER SIERRA ; DE MELLO JUNIOR, LEÔNIDAS JOÃO ; SILVA, ADNY HENRIQUE ; GUALBERTO, ANA ; GAMEIRO, JACY ; Dittz, Dalton ; PASA, ANDRÉ AVELINO ; PITTELLA, Frederico ; CRECZYNSKI-PASA, TÂNIA BEATRIZ . Short interfering RNA delivered by a hybrid nanoparticlße targeting VEGF: Biodistribution and anti-tumor effect. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, v. 1865, p. 129938, 2021.

RIBEIRO, M. C. S. ; MIRANDA, M. C. ; CUNHA, P. S. ; ANDRADE, G. F. ; FULGENCIO, G. O. ; GOMES, D. A. ; FIALHO, S. L. ; PITTELLA, F. ; CHARRUEAU, C. ; ESCRIOU, V. ; SILVA-CUNHA, A. . Neuroprotective Effect of siRNA Entrapped in Hyaluronic Acid-Coated Lipoplexes by Intravitreal Administration. PHARMACEUTICS, v. 13, p. 1-18, 2021.

SILVA, LÍVIA MARA ; MARCONATO, DANIELLE GOMES ; NASCIMENTO DA SILVA, MARCOS PAULO ; BARBOSA RAPOSO, NÁDIA REZENDE ; FARIA SILVA FACCHINI, GABRIELA DE ; MACEDO, GILSON COSTA ; TEIXEIRA, FERNANDA DE SÁ ; BARBOSA DA SILVEIRA SALVADORI, MARIA CECÍLIA ; FARIA PINTO, PRISCILA DE ; MORAES, JOSUÉ DE ; PITTELLA, Frederico ; DA SILVA FILHO, ADEMAR ALVES . Licochalcone A-loaded solid lipid nanoparticles improve antischistosomal activity in vitro and in vivo. Nanomedicine, v. 16, p. 1641-1655, 2021.

OLIVEIRA, T. D. ; RIANI, LORENA RODRIGUES ; COSTA, M. P. ; FABRI, R. L. ; NASCIMENTO, J. W. L. ; SILVA, F. P. ; SILVA FILHO, A. A. ; TAVARES, G. D. . Baccharis dracunculifolia extract-loaded chitosan nanoparticles: development, physicochemical characterization and cytotoxicity evaluation. Brazilian Journal of Development, v. 7, p. 72010-72022, 2021.

FERREIRA, KÉZIA CRISTINE BARBOSA ; VALLE, ANA BEATRIZ CARIBÉ DOS SANTOS ; PAES, CAMILA QUINETTI ; TAVARES, GUILHERME DINIZ ; PITTELLA, Frederico . Nanostructured Lipid Carriers for the Formulation of Topical Anti-Inflammatory Nanomedicines Based on Natural Substances. PHARMACEUTICS, v. 13, p. 1454, 2021.

OLIVEIRA, T. D. ; RIANI, L. ; COSTA, M. P. ; FABRI, R. L. ; NASCIMENTO, J. W. L. ; SILVA, F. P. ; SILVA FILHO, A. A. ; TAVARES, G. D. . Baccharis dracunculifolia extract-loaded chitosan nanoparticles: development, physicochemical characterization and cytotoxicity evaluation. Brazilian Journal of Development, v. 7, p. 72010-72022, 2021.

LIVEIRA, T. D. ; RIANI, LORENA RODRIGUES ; COSTA, M. P. ; FABRI, R. L. ; NASCIMENTO, J. W. L. ; SILVA, F. P. ; SILVA FILHO, A. A. ; TAVARES, G. D. . Baccharis dracunculifolia extract-loaded chitosan nanoparticles: development, physicochemical characterization and cytotoxicity evaluation. Brazilian Journal of Development, v. 7, p. 72010-72022, 2021.

2020

CRISTOFOLINI, TATIANE ; DALMINA, MILENE ; SIERRA, JELVER A. ; SILVA, ADNY H. ; PASA, ANDRÉ A. ; PITTELLA, Frederico ; CRECZYNSKI-PASA, TÂNIA B. . Multifunctional hybrid nanoparticles as magnetic delivery systems for siRNA targeting the HER2 gene in breast cancer cells. Materials Science & Engineering C-Materials for Biological Applications, v. 109, p. 110555, 2020.

PITTELLA, Frederico; DE OLIVEIRA, BRUNA ALVES ; FERREIRA, KÉZIA CRISTINE BARBOSA ; RAPOSO, NÁDIA REZENDE BARBOSA . Preparação de sistemas nanoparticulados para a solubilização e incorporação de ativos hidrofóbicos. PRINCIPIA (JUIZ DE FORA), v. 18, p. 10, 2020.

LEITE, FERNANDA BRITO ; SANTOS-VALLE, ANA BEATRIZ C. ; PAES, CAMILA QUINETTI ; PITTELLA, Frederico . Avaliação de metodologias para a reutilização de membranas de nanocelulose bacteriana como scaffold para cultura celular. PRINCIPIA (JUIZ DE FORA), v. 19, p. 10, 2020.

FASOLATO, ANA CAROLINA MARCIAL ALVES ; PITTELLA, Frederico . Desenvolvimento de nanocarreadores com base em carbonato de cálcio visando a entrega de short interfering RNA em câncer de mama. PRINCIPIA (JUIZ DE FORA), v. 19, p. 9, 2020.

DOS SANTOS VALLE, ANA BEATRIZ CARIBÉ ; GUALBERTO, ANA C.M. ; PITTELLA, F . Short Interfering RNA (siRNA) based Medicines and the Future of RNAi Therapy: A Mini Review. Current Trends in Biomedical Engineering & Biosciences, v. 19, p. 556022, 2020.

DA SILVA, NATÁLIA PRADO ; CARMO RAPOZO LAVINAS PEREIRA, ELOÁ DO ; DUARTE, LUCAS MATTOS ; DE OLIVEIRA FREITAS, JHAMINE CAROLINE ; DE ALMEIDA, CAMILA GUIMARÃES ; DA SILVA, THIAGO PEREIRA ; DE MELO, ROSSANA CORREA NETTO ; MORAIS APOLÔNIO, ANA CAROLINA ; DE OLIVEIRA, MARCONE AUGUSTO LEAL ; DE MELLO BRANDÃO, HUMBERTO ; PITTELLA, Frederico ; FABRI, RODRIGO LUIZ ; TAVARES, GUILHERME DINIZ ; DE FARIA PINTO, PRISCILA . Improved anti-Cutibacterium acnes activity of tea tree oil-loaded chitosan-poly(ε-caprolactone) core-shell nanocapsules. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 196, p. 111371, 2020.

PALMIEIR, M. G. S. ; FERREIRA, K. ; VALLE, A. B. C. S. ; ALEIXO, D. T. ; TAVARES, G. D. ; CORREA, J. O. A. ; SILVA, F. P. . Development of nanostructured lipid carriers containing finasteride. Brazilian Journal of health and Pharmacy, v. 2, p. 20-29, 2020.

SANTOS, M. M. ; FERREIRA, K. C. B. ; VALLE, A. B. C. S. ; DINIZ, I. O. M. ; FABRI, R. L. ; SILVA, F. P. ; TAVARES, G. D. . Physicochemical and biological evaluation of clotrimazole loaded nanoemulsion as a therapeutic alternative for treatment of vulvovaginal candidiasis. Brazilian Journal of Health and Pharmacy, v. 2, p. 60-68, 2020.

LEMOS, A. ; FLORENCIO, J. ; PINTO, N. ; MELO, L. ; SILVA, T. ; GRAZUL, R. ; PINTO, P. ; TAVARES, G. D. ; SCIO, E. ; APOLONIO, A. C. ; MELO, R. ; FABRI, R. L. . Antifungal activity of the natural coumarin scopoletin against planktonic cells and biofilms from a multidrug-resistant Candida tropicalis strain. Frontiers in Microbiology, v. 11, p. 1525, 2020.

PRADO, R. ; BERTGES, F. S. ; FIGUEIREDO, S. A. ; FONSECA, M. J. V. ; TAVARES, G. D. ; VILELA, F. M. P. . Photostability of commercial sunscreens upon sunlight exposure. HU REVISTA (UFJF. IMPRESSO), v. 46, p. 1-9, 2020.

CAMPOS, L. ; LEMOS, A. S. O. ; CRUZ, L. F. ; ARAUJO, M. G. F. ; BOTTI, G. C. R. M. ; REIS JUNIOR, J. L. ; ROCHA, V. N. ; DENADAI, A. M. L. ; SILVA, T. P. ; TAVARES, G. D. ; SCIO, E. ; FABRI, R. L. ; PINTO, P. F. . Development and in vivo evaluation of chitosan-gel containing Mitracarpus frigidus methanolic extract for vulvovaginal candidiasis treatment. BIOMEDICINE & PHARMACOTHERAPY, v. 130, p. 110609, 2020.

SANTOS, T. S. ; CORDEIRO, M. R. ; FONSECA, L. N. ; VAZ, U. P. ; VILELA, F. M. P. ; TAVARES, G. D. . Desenvolvimento de preparação extemporânea de uso pediátrico contendo furosemida. HU REVISTA (UFJF. IMPRESSO), v. 46, p. 1-7, 2020.

TAVARES, G. D.; GONCALVES, J. E. ; MONTEIRO, L. M. ; LOEBENBERG, R. ; STORPIRTIS, S. ; BOU-CHACRA, N.A.; CONSIGLIERI, V. O. . N,N,N-trimethylchitosan-poly (n-butylcyanoacrylate) core-shell nanoparticles as a potential oral delivery system for acyclovir. COLLOIDS AND SURFACES B-BIOINTERFACES, p. 111336, 2020.

CERQUEIRA, A. F. L. W. ; NEIVA, G. P. ; FERNANDES, M. F. ; CONEGUNDES, J. L. M. ; STEPHANI, R. ; OLIVEIRA, L. F. C. ; LUDWIG, Z. M. C. ; ANJOS, V. C. ; VILELA, F. M. P. ; SCIO, E. ; TAVARES, G. D. ; RODARTE, M. P. . Influence of the xanthan gum as a crosslinking agent on the physicochemical properties of chitosan microparticles containing green coffee extract. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, v. 29, p. 101782, 2020.

2019

SANTOS-VALLE, A. B. C.; SOUZA, G. R. R.; PAES, C. Q.; MIYAZAKI, T.; SILVA, A. H.; ALTUBE, M. J.; MORILLA, M. J.; ROMERO, E. L.; CRECZYNSKI-PASA, T. B.; CABRAL, H.; PITTELLA, F. Nanomedicine strategies for addressing major needs in neglected tropical diseases. ANNUAL REVIEWS IN CONTROL, in press, 2019. DOI: 10.1016/j.arcontrol.2019.08.001.

DALMINA, M.; PITTELLA, F.; SIERRA, J. A.; SOUZA, G. R. R.; SILVA, A. H.; PASA, A. A.; CRECZYNSKI-PASA, T. B. . Magnetically responsive hybrid nanoparticles for in vitro siRNA delivery to breast cancer cells. Materials Science & Engineering C, v. 99, p. 1182-1190, 2019.

ALABI, O. A.; SILVA, A. H.; PURNHAGEN, L. R. P.; SOUZA, G. R. R.; DE MELLO JÚNIOR, L. J.; FILIPPIN-MONTEIRO, F. B.; DALMINA, M.; PITTELLA, F.; BAKARE, A. A.; CRECZYNSKI-PASA, T. B. . Genetic, reproductive and oxidative damage in mice triggered by co-exposure of nanoparticles: From a hypothetical scenario to a real concern. SCIENCE OF THE TOTAL ENVIRONMENT, v. 660, p. 1264-1273, 2019.

COSTA, J. S. R. ; MEDEIROS, M. ; YAMASHIRO-KANASHIRO, E. H. ; ROCHA, M. C. ; COTRIM, P. C. ; STEPHANO, M. A. ; LANCELLOTTI, M. ; TAVARES, G. D. ; NASCIMENTO, L. . Biodegradable nanocarriers coated with polymyxin B: evaluation of leishimanicidal and antibacterial potential. PLoS Neglected Tropical Diseases, v. 13, p. 1-15, 2019.

2018

SANTOS, M.; DOS SANTOS VALLE, A. B. C.; MOURA GUALBERTO, A. C.; LEITE, F. B.; PITTELLA, F. . Setting Precise Temperature for Triggered Release from Nanostructured Lipid Carriers. IFAC-PAPERSONLINE, v. 51, p. 1-6, 2018.

SOLDATI, P. P.; POLONINI, H. C.; PAES, C. Q.; RESTREPOB, J. A. S.; CRECZYNKSI-PASA, T. B.; CHAVES, M. G. A. M.; BRANDÃO, M. A. F.; PITTELLA, F.; RAPOSO, N. R.B. . Controlled release of resveratrol from lipid nanoparticles improves antioxidant effect. IFAC-PAPERSONLINE, v. 51, p. 16-21, 2018.

DE MELLO, L. J.; SOUZA, G. R.R.; SILVA, A. H.; GUALBERTO, A. C. M.; GAMEIRO, J.; JÚNIOR, D. D.; DE MIRANDA, N. B. ; PITTELLA, F.; CRECZYNSKI-PASA, T. B. . In vivo antiapoptotic gene silencing: hybrid nanoparticles as delivery system. IFAC-PAPERSONLINE, v. 51, p. 10-15, 2018.

MORAES, A. ; TAVARES, G. D. ; ROCHA, F. ; PAULA, E. ; GIORGIO, S. . Effects of nanoemulsions prepared with essential oils of with andiroba- and copaiba against Leishmania infantum and Leishmania amazonensis infections. EXPERIMENTAL PARASITOLOGY, v. 187, p. 12-21, 2018.

2017

PENA, M. G. R.; COELHO, M. O.; PITTELLA, F.; FURTADO, M. A. M.; NASCIMENTO, W. W. G.; COSTA, F. F. . Produccion de micro y nanoparticulas a base de biopolimeros naturales: estudio de la estabilidad de emulsiones a base de suero lacteo. Tecnología Láctea Latinoamericana, v. 98, p. 48-58, 2017.

MELLO JUNIOR, L.; SOUZA, G.R.; WINTER, E.; SILVA, A.H.; PITTELLA, F.; CRECZYNSKI-PASA, T.B. Knockdown of Antiapoptotic Genes in Breast Cancer Cells by siRNA Loaded Into Hybrid Nanoparticles. Nanotechnology (Bristol), v.28, p.175101 ,2017.

2015

BARBOSA, S. F.; TAKATSUKA, T.; TAVARES, G. D.; ARAUJO, G. L. B.; WANG, H.; VEHRING, R.; LOEBENBERG, R.; BOUCHACRA, N. A. Physical–chemical properties of furosemide nanocrystals developed using rotation revolution mixer. Pharmaceutical Development and Technology (Print). , v.21, p.1 11, 2015.

NAEEM, M.; REHMAN, N. U.; TAVARES, G. D.; BARBOSA, S. F.; BOUCHACRA, N. A.; LOBENBERG, R.; SARFRAZ, M. Physicochemical, in vitro and in vivo evaluation of flurbiprofen microemulsion. Anais da Academia Brasileira de Ciências (Impresso). , v.87, p.1823 1831, 2015.

MONTEIRO, L. M.; TAVARES, G. D.; FERREIRA, E. I.; CONSIGLIERI, V.O.; BOUCHACRA, N. A.; LOEBENBERG, R. Reverse phase highperformance liquid chromatography for quantification of hydroxymethylnitrofurazone in polymeric nanoparticles. Brazilian Journal of Pharmaceutical Sciences (Online). , v.51, p.561 567, 2015.